Scientist, Molecular Biology at Relay Therapeutics
Cambridge, MA, US
Our company was founded on the premise that protein motion can be used to build breakthrough medicines. The team at Relay is putting this principle into practice, with the aim of accelerating the development of medicines that will make a transformative difference in patients’ lives. We don't just stare hard problems in the face. We go out looking for them. Are you energized by attempting to do the impossible? We're looking for you.
At Relay, our team is energized by the ultimate collaboration between biology, chemistry, computation, and biochemistry & biophysics.  Putting protein motion at the heart of drug discovery is a challenge, but we are confident that our team’s dedication and urgency will create opportunities that deeply impact the lives of the patients. We're building a company for the ages. Are you ready to #jointherelay?

The opportunity

    • We are seeking a creative, collaborative, and motivated PhD molecular biologist to join our growing Biology team.  At Relay we apply cutting edge technology towards the discovery, characterization, and optimization of small molecule therapeutics towards oncology targets representing high, unmet medical needs. The successful candidate will work independently within a team to evaluate target dependency hypotheses, develop and optimize cell-based assays to enable screening and evaluation of small molecule leads, and help identify preclinical models, representative of target patient populations.  

Your role

    • Independently design and execute experiments to evaluate target dependency and conformational hypotheses by skillfully employing molecular cloning, CRISPR/Cas9, knockdown/overexpression, and mutagenesis screen approaches.
    • Assess both mechanism and small molecule modulation of cancer targets, including hit identification, validation, and optimization. Spearhead efforts on development and optimization of cell-based assays of various formats. Experience with microscopy, FACS, and luminescence will be useful.
    • Identify preclinical models that reflect patient pathology and perform pathway profiling.
    • Interpret, summarize, and present research findings at internal and external scientific meetings/conferences.
    • Proactively review literature to bring in the newest scientific findings, ideas, and methods/technologies for discovery research.

Your background

    • You have earned a Ph.D. and 1-3 years post-doctoral training in Cancer Biology
    • You have proven track record of excellence as evidenced by high impact, peer reviewed publications
    • You have a solid skill set in molecular and cellular biology techniques
    • Experience with in vitro pharmacological assessment of small molecules preferred
    • You work collaboratively within a dynamic matrix environment, with strong contribution to project strategies and progression
    • You have excellent communication, presentation, and inter-personal skills
    • You are eager to deepen the understanding of the small molecule drug discovery process
At Relay, we believe that along with our scientists, our culture is our greatest asset.  In fact we're proud to share we were named as one of the Boston Business Journal's "Best Places to Work" in 2017 & the #1 place for small companies in 2018.   To drive that culture, no one will stop you or hold you back. Instead, we will give you the tools and colleagues to push forward relentlessly and cheer you on as you go. If this resonates with you, drop us a line.
Relay Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.