Senior / Research Associate, Synthetic Chemistry at Relay Therapeutics
Cambridge, MA, US
Relay Therapeutics was founded on the premise that protein motion can be leveraged to create breakthrough medicines, with a drug discovery engine that was built on advances in detecting and characterizing dynamic interactions - anywhere on a protein – not just at the active site. Our team is putting this principle into practice, with the aim of accelerating the development of medicines that will make a transformative difference in patients’ lives. We don’t just stare hard problems in the face – we go out looking for them. Are you energized by attempting to do the impossible?  We’re looking for you!
Energized by the ultimate collaboration between chemistry, biology, computation, and biochemistry & biophysics, we have the resources to change the way drugs are discovered and help millions of people who were previously untreatable. While leveraging protein motion for drug discovery is a challenge, we are confident that our team’s dedication and urgency will create opportunities that deeply impact the lives of the patients. We’re building a company for the ages.

The opportunity

      • We are looking for a self-motivated researcher with a strong background in Synthetic Chemistry to support our Medicinal Chemistry team. You will have access to some of the smartest people you’ve ever worked with and all the tools and resources you need to do the best work of your career.
      • We take what we do seriously, but we don’t take ourselves too seriously.  You’ll have fun in our collaborative and energetic environment where you’ll face new challenges every day.
    • If you are flexible and fearless in the face of rapidly evolving data, then we want you to join us and discover the next generation of innovative therapeutics based on protein motion!

Your role

    • You’ll take a key role in Relay’s design, synthesis and purification of small molecule therapeutics. Within this role, you will independently design synthetic routes and solve complex synthetic problems. We also look for you to lead the synthetic effort of program teams into new areas and to demonstrate a high level of creativity and productivity at the bench.
    • We’ll depend on you to be up to date on the scientific literature to bring in the newest scientific findings, ideas and methods or technologies for discovery research.
    • You can expect that analysis, interpretation, documentation as well as presentation within our group and project teams will be part of your day. You may also be asked to present your team’s work at external meetings and scientific conferences. 
    • You will work closely and collaborate in a multi-disciplinary team.
    • Your voice is important, and we will count on you to contribute to group knowledge and expertise through collaboration and idea exchange across teams.

Your background

    •  You earned a Bachelor’s or Master’s degree in chemistry with an emphasis on synthetic organic chemistry or a related field.
    • You have spent 3 or more years gaining relevant industry experience in supporting medicinal chemistry with an emphasis on route scouting, scale up, process chemistry or library synthesis.
    • You have a proven track record of excellence as exhibited by high impact, peer-reviewed publications and/or patents. 
    • You have superior laboratory skills and proficiency in experimental design.
    • You are comfortable with using predictive tools to enable your compound designs.
    • You are self-motivated with a proactive mindset.
    • You enjoy working independently as well as interacting with a multidisciplinary team of structural biologists, biophysicists, biologists, computational chemists, pharmacologists, and external collaborators.
    • You are committed to building an energetic, collaborative and open company culture and contributing to the company’s success. 
At Relay, we believe that along with our people, our culture is our greatest asset. In fact, we’re proud to share we were named as one of the Boston Business Journal’s "Best Places to Work" in 2017 and we are the  #1 place for small companies in 2018! To drive that culture, no one will stop you or hold you back. Instead, we will give you the tools and colleagues to push forward relentlessly and cheer you on as you go. If this is what you are looking for – drop us a line.
Relay Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.