Senior Scientist at Decibel Therapeutics
Boston, MA, US
Position Overview and Responsibilities:

As the Senior Scientist, you will be expected to work equally well in self-starting mode as well as a member of a matrixed team within Decibel. Your initial focus will be to develop, implement and execute appropriate in vivo and/or in vitro assays required for the advancement of both specific high priority projects as well as Decibel’s inner ear platform. As one of the key early hires for the company, you will work in close collaboration with the management team and scientists to ensure that our pre-clinical programs and technology platform are based on solid scientific foundations, accurate feasibility assessments, and grounded in realistic, corporate aligned goals.


PhD in pharmacology, neurobiology, molecular and/or cell biology with 3 to 5+ year’s relevant experience or BA or MA with 12 to 15+ year’s relevant industry experience
At least 5 years of experience working on early-stage and IND-enabling teams within the pharmaceutical industry
Hands-on experience in diverse, in vivo and in vitro experimental model systems, histology and RNA/protein expression techniques
Deep expertise in regenerative medicine strategies, preferably in the inner ear
Broad vocabulary that encompasses significant (publications and/or INDs) experience in other hearing-related fields (e.g. at least one of tinnitus, noise-induced hearing loss, ototoxicity, presbycusis, genetic disorders relevant to hearing)
Proven track record in new assay and high-through put assay development
Strong problem-solving skills
Ability to be productive in a fast-paced, team-work, multi-task environment
Ability to function equally well in self-starter mode as well as a member of a matrixed team
Outstanding interpersonal and communication skills

Knowledge, Skills, and Abilities:

Independently design, execute, troubleshoot, and interpret biological experiments in support of program objectives
Prepare protocols and SOPs for diverse assays
Maintain accurate documentation of experiments
Interact and communicate results and conclusions within the biology/pharmacology group and cross functional project teams
Review the scientific literature to remain abreast of developments in relevant fields

Preference will be given to candidates who additionally have:

Expertise in in vitro (cell lines and explants) models relevant to the inner ear with proven track record in assay development, implementation and execution
Detailed familiarity with cochlear anatomy and physiology, in vivo and/or in vitro models of inner ear function, inner ear imaging techniques, inner ear histopathology, electrophysiology
Deep expertise in regenerative medicine strategies, preferably in the inner ear