Senior Research Associate, Protein Analytics at Magenta Therapeutics
Cambridge, MA, US
Magenta is seeking a highly-motivated individual with proven experience in the analytical and formulation development of antibodies, antibody fragments and antibody drug conjugates. The successful candidate will play an integral role in the discovery and development of transformative biotherapeutics for hematopoietic stem cell transplant therapies. The ideal candidate will provide analytical support to the biotherapeutics drug discovery department.
Minimum requirements:
• Bachelors or Masters in biochemistry, biotechnology, chemistry, pharmaceutical or biological sciences
• The ideal candidate will have 3-5 years of experience in biotech/ pharma with a thorough understanding of the analytical/developability aspects of biotherapeutics drug discovery
• Strong experience with analytical techniques such as HPLC (SEC, reverse phase, ion-exchange, hydrophobic interaction, CIC), CE-SDS, CE-iEF, UV/CD/FTIR, AC-SINS, Western blot, SDS-PAGE, ELISA etc.
• Experience with the characterization of antibodies by mass spectrometry is preferred
• Strong understanding of the biophysical and chemical behavior of antibodies under a variety of stresses
• Working knowledge and experience with biologics including antibody drug conjugates is a plus
• Ability to design and execute experiments independently
• Must be able to meet deadlines in a fast-paced, start-up environment
• Deep understanding of bioconjugation principles and formulation development of biologics including antibody drug conjugates will be favorably considered
• Excellent interpersonal, communication, and problem-solving skills are required
• Relevant experience with early stage and late stage development of biologics is preferable
We offer competitive compensation along with a comprehensive benefits package. To apply, please submit your resume.