Research Associate / Senior Research Associate, Biology at Relay Therapeutics
Cambridge, MA, US
Position Summary

Relay Therapeutics is seeking a self-motivated researcher a desire to excel at the highest level to join a team of scientists driving the discovery of novel small molecule therapeutics in oncology. The successful candidate will design and execute molecular and cell biology experiments focused on the discovery/validation of new drug targets, evaluation of candidate molecules, and development of novel biomarkers. A considerable level of independence is expected after the initial training period. S/he will interact and collaborate cross-functionally with scientists in other departments, including biochemists, chemists, and computational biologists. Significant project ownership will allow for acquisition of new skills and for learning additional facets of the drug discovery process as projects advance.

Job Responsibilities

Design and perform cell and molecular biology experiments to support the biological evaluation of small molecules impacting cancer dependencies and anti-cancer immunity
Develop cell-based assays to be used in target validation studies and/or medium throughput screening campaigns
Conduct cell-based assays in support of medicinal chemistry efforts and structure activity relationship assessment
Develop and perform pharmacodynamic and patient selection biomarker assays
Maintain good written records of laboratory procedures, results and conclusions.
Perform and report interim analysis of accumulated data to monitor work progress.

BS/MS with 3+ years of industry/academic experience working in a cancer biology team
Experience in molecular biology (nucleic acid purification, DNA cloning, PCR, gel electrophoresis, Western blotting, and qPCR, si/shRNA, CRISPR, lentiviral gene knockdown)
Exceptional cell biology capabilities (mammalian cell culture flow cytometry, microscopy). Experience with in vitro immunology assays is a plus
Ability to design and execute experiments, analyze and document results
Excellent organizational and communication skills
Excellent problem-solving skills and ability to multi-task