Discovery Biology Director at Tango Therapeutics
Cambridge, MA, US
Position Summary:

Tango Therapeutics is looking for a highly creative and self-motivated Ph.D scientist with adamant intellectual curiosity and a drive to excel at the highest level to lead a team of scientists aiming to fulfill the promise of next generation cancer therapeutics. The successful candidate will work independently within in a team to discover/validate drug targets and gain insights on pathway biology. We want consummate team players who seek a highly scientifically rigorous environment for their career development in drug discovery.

Job Responsibilities:

Independently design, develop and execute cancer biology experiments focused on identification and validation of new drug targets, and drive responder hypothesis and PD/biomarker discovery in a team environment.
Proactively review literature to bring in newest scientific findings, ideas, and methods/technologies for discovery research.
Work cross-functionally with chemistry and High Throughput Screening to develop cell based assays and lead development and optimization
Responsible for facilitating drug discovery process from discovery through pre-clinical development
Interpret, summarize and present research findings in internal and external scientific meetings/conferences
Capability to lead a biology project, actively participate in and collaborate with multidisciplinary drug discovery teams

Ph.D/MD in Cell & Molecular Biology or Genetics, plus 5-10 years academic or industry experience with high impact, peer reviewed publications and a proven track record of productivity and creativity
Proven project/ program leadership skills leading projects in biotech/ pharmaceutical industry
Familiarity and proven experience with managing IND-enabling studies and managing programs from discovery to the clinic
Exceptional cell biology skills (incl mammalian cell culture, flow cytometry, and microscopy), and expertise in cancer biology
Capability to work within a dynamic matrix environment, with strong contribution to project strategies and progression
Excellent communication, presentation, and inter-personal skills; superb organizational and problem-solving skills
Leadership in drug discovery development and expertise in oncology including translation from primary research through validation. Understanding of molecule development including understanding of in vivo pharmacology, DMPK and Toxicology needed.