Careers

Scientist, Hearing Biology at Decibel Therapeutics
Boston, MA, US
Position Overview and Responsibilities:
As a Scientist, Hearing Biology you will be expected to work equally well in self-starting mode as well as a member of a matrixed team within Decibel. Your initial focus will be to develop, implement and execute appropriate in vivo and/or in vitro assays required for the advancement of both specific high priority projects as well as Decibel’s inner ear platform. As one of the key early hires for the company, you will work in close collaboration with the management team and scientists to ensure that our pre-clinical programs and technology platform are based on solid scientific foundations, accurate feasibility assessments, and grounded in realistic, corporate aligned goals.

Requirements:

PhD in neurobiology, molecular and/or cell biology with 1 to 3+ year’s relevant experience or BA or MA with to 3-6+ year’s relevant industry experience
Hands-on experience in diverse, in vivo and in vitro experimental model systems, surgical approaches for delivery to the inner ear, AAV gene delivery, dissection and histology of the adult inner ear, microscopy, and RNA/protein analysis
Broad vocabulary that encompasses significant (publications and/or INDs) experience in other hearing-related fields (e.g. at least one of tinnitus, noise-induced hearing loss, ototoxicity, presbycusis, genetic disorders relevant to hearing)
Strong problem-solving skills
Ability to be productive in a fast-paced, team-work, multi-task environment
Ability to function equally well in self-starter mode as well as a member of a matrixed team
Outstanding interpersonal and communication skills
Knowledge, Skills, and Abilities:

Independently design, execute, troubleshoot, and interpret biological experiments in support of program objectives
Prepare protocols and SOPs for diverse assays
Maintain accurate documentation of experiments
Interact and communicate results and conclusions within the biology/pharmacology group and cross functional project teams
Review the scientific literature to remain abreast of developments in relevant fields
Preference will be given to candidates who additionally have:

Expertise in in vitro (cell lines and explants) models relevant to the inner ear with proven track record in assay development, implementation and execution
Detailed familiarity with cochlear anatomy and physiology, in vivo and/or in vitro models of inner ear function, AAV delivery to the inner ear, inner ear imaging techniques, microdissection of the adult inner ear, inner ear histopathology, electrophysiology

To be considered for a position at Decibel Therapeutics, please submit your CV with the title of the position in the subject line.