Research Associate/Sr. Research Associate, in vivo at Magenta Therapeutics
Cambridge, MA, US
About the Company

Magenta Therapeutics is a biotechnology company harnessing the power of stem cell science to revolutionize stem cell transplantation for patients with immune and blood-based diseases. By creating a platform focused on critical areas of transplant medicine, Magenta Therapeutics is pioneering an integrated approach to stem cell therapies to create patient benefits. Founded by internationally recognized leaders in stem cell transplant medicine, Magenta Therapeutics was launched in 2016 by Third Rock Ventures and Atlas Venture and is headquartered in Cambridge, Mass. For more information, please visit

Position Overview

The successful candidate will be an integral member of a team developing novel therapeutics to transform hematopoietic stem cell transplantation. This challenging opportunity requires in depth knowledge of mouse models of hematologic, oncology, or immune diseases as well as in depth knowledge of human hematopoietic stem cell biology, and hematopoietic disease models. This position will involve translational research in hematopoietic stem cell biology.

Primary Responsibilities:

Design, plan, and execute in vivo pharmacology studies to evaluate efficacy, pharmacokinetic, pharmacodynamic, tolerability and mechanism of action of drug candidates
Perform ex vivo assays to help broaden our understanding of how our therapeutic leads can affect normal immune function and autoimmune disease
Analyze and present scientific data, engage colleagues in cross-disciplinary scientific discussion, and stay abreast of relevant scientific literature

BS, BA, or MS degree in a relevant field (pharmacology, immunology, oncology, biology) with 1-5 years of relevant research experience, industry experience is a strong plus
Expertise working with murine models of autoimmune, oncology, and/or hematologic disease is required. Humanized mouse experience is a plus
Proficient in animal handling, dosing (IV, IP), blood collection, and tissue harvesting
Experience with multiple molecular techniques (FC, ELISA, PCR, real-time PCR, western blot, etc.) is highly desirable
The position requires excellent written and verbal communication skills and the ability to work effectively both independently and as part of multi-disciplinary team
Must be a scientifically motivated self-starter, capable of independently conceiving, conducting, and critically analyzing his/her own innovative research with minimal supervision
Strong presentation skills, communication and the ability to work in a fast-paced and team-oriented environment will also be vital
Demonstrated understanding of immunology and blood biology is highly desirable
We offer competitive compensation along with a comprehensive benefits package. To apply, please submit your resume and include the job title in the subject of your email.