Scientist, In Vivo Electrophysiology at Decibel Therapeutics
Boston, MA, US
Position Overview & Responsibilities:

Decibel Therapeutics is looking for a Scientist with experience in the auditory system to be part of the pharmacology team working to identify novel therapies for the treatment of hearing loss.

As a Scientist, you will be expected to work equally well as a self-starter and as a member of a matrixed team within Decibel. Your focus will be to develop and execute appropriate in vivo assays required for the advancement of specific high priority projects as well as Decibel’s inner ear platform. You will work in close collaboration with the management team and scientists to ensure that our pre-clinical programs and technology platform are based on solid scientific foundations, accurate feasibility assessments, and are grounded in realistic, corporate aligned goals.

In this position you will lead the design and execution of in vivo pharmacology studies to determine the efficacy profile of novel compounds and their potential to treat hearing loss, using a variety of assays. In addition, you will be responsible for data analysis and interpretation and formulating the path for advancement through Decibel’s discovery programs.

The individual in this position will have the opportunity to work closely with biology, drug delivery/PK and translational research teams, across multiple projects and indications.

The successful candidate will be highly motivated to work as part of a team in a fast-paced, dynamic environment. Additionally, the ideal candidate will be highly enthusiastic to join the wider Decibel team in working to understand the bases of hearing losses and to generate treatments that benefits patients, their families and communities.


PhD in pharmacology, molecular and/or cell biology or neurobiology with 3 to 5+ years relevant experience or Bachelors or Master’s degree with 12 to 15+ year’s relevant industry experience
Hands-on experience with in vivo electrophysiology (field potentials, multi-unit, or single-unit), including data acquisition, analysis, and visualization
Hands-on experience in diverse, in vivo and in vitro experimental model systems, molecular and cell biology, cell signaling and RNA/protein expression techniques
Experience in designing and executing experimental strategies to validate and understand the mechanism of action for identified targets
Broad vocabulary that encompasses significant (publications and/or INDs) experience in hearing-related fields (e.g. at least one of: tinnitus, noise-induced hearing loss, ototoxicity, presbycusis, genetic disorders relevant to hearing) or other indications
Ability to develop and execute research studies, critically assess data quality and results, and effectively communicate results to the team
Strong problem-solving skills
High level of interpersonal skills, including working/communicating with multiple teams
Ability to time-manage and work on multiple projects
Ability to work in a dynamic environment