Scientist, Immune Monitoring at Neon Therapeutics
Cambridge, MA, US
Position Summary

Neon is seeking a highly-motivated Scientist to join Neon’s Immune monitoring group. The candidate will work within the Immune monitoring group in close collaboration with other scientists in the group and with other groups at Neon. The group is focused on translational immunology and he/she will work directly with the clinical samples generated during Neon Trials. He/she will work independently as well as part of a multi-disciplinary research team to develop different immune monitoring assays and data.

Job responsibilities include:

Collaborate with both internal research teams and external groups/ CROs to advance Immune-monitoring capabilities at Neon.
Develop Immune monitoring strategies for Neon sponsored clinical trials.
Design and perform Immune Monitoring assays like ELISAs, ELISPOTS, Fluorescence activated cell sorting analysis, mass cytometry and T cell proliferation assays.
Purification and characterization of PBMCs and tumor infiltrating lymphocytes from peripheral blood and lymphocytes.
Evaluation of T cell receptor sequences in TILS and PBMCS
Develop SOPS and maintain a high standard of experimentation and record keeping
Improvement of current processes and implementation of new technologies.
Analysis and presentation of results to larger scientific groups.
Train and supervise research associates to accomplish program and company goals.
Work productively in a team environment and independently and deliver against timelines.
Experience and essential skills:

Ph.D., M.D., or M.D./Ph.D in Immunology with a minimum of 5 years of working experience in academia or industry.
Expert in immunology and development of immune related assays.
Strong experience in FACS and prior experience in mass cytometry preferred.
Deep knowledge of T cell biology, and experience in cell culture work.
Prior experience working with immuno-oncology systems preferred.
Experience in a clinical lab highly desirable.
Demonstrated experience in complex problem solving.
Excellent organizational, communication skills and a pro-active mentality.
Excellent attention to detail.
Demonstrated experience functioning within a multi-disciplinary team and ability to integrate cross-functional information, to optimize work flows.