Senior Scientist, Drug Metabolism and Pharmacokinetics at Revolution Medicines
Redwood City, CA, US
REVOLUTION Medicines discovers and develops new drugs that translate frontier cancer targets through exceptional drug discovery delivering revolutionary medicines on behalf of cancer patients. Our innovative science draws inspiration from nature and evolution, which offer insights into cancer targets, disease mechanisms and therapeutic approaches. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.

As a Senior Scientist in DMPK, you will:

Be a critical contributor to the Development Sciences organization and multi-disciplinary research project teams.

Design, conduct, and manage in vitro and in vivo ADME, PK, PK/PD and TK studies in-house or at contract research organizations (CROs).

Analyze, interpret data and present results to cross functional project teams to ensure timely data based decision making.

Represent DMPK in core project teams and be responsible for leading the scientific, technical, and operational efforts of the DMPK function to support discovery and early development projects.

Develop high-quality protocols and maintain detailed documentation of procedures and data to comply with internal standard operating procedures and other quality criteria, where necessary.

Required Skills
A Ph.D. in Pharmaceutical Sciences, Pharmacokinetics, Drug Metabolism, or a related field with at least 3 years of relevant industry experience in supporting small molecular lead optimization, candidate selection and early development.

Strong scientific knowledge and hands-on experience in designing/conducting in vitro and in vivo ADME/PK studies.

Extensive hands-on experience in small molecule bioanalysis using LC/MS/MS.

Experience in managing CROs.

Experience representing the DMPK function on project teams.

Experience in regulatory filing is desired.

Excellent written and verbal communication skills.

Thrives in a collaborative team setting and is driven by a desire to be innovative in a high energy, small company environment.