Senior Research Associate - Associate Scientist, T Cell Immunology at Neon Therapeutics
Cambridge, MA, US

 Company Summary


Neon Therapeutics is focused on unlocking the full potential of the immune system to recognize and attack cancer. We have assembled a team of world experts in cancer immunotherapy to develop therapies that target mutant proteins, known as neoantigens, which are produced by cancer cells. Our programs are designed to leverage multiple facets of immune memory to elicit potent immune attack of tumors, with the aim of providing durable response to patients in need.


Position Summary


Neon is seeking a highly-motivated Senior Research Associate/Associate Scientist with the goal of developing a neoantigen specific T cell product to be used in adoptive T cell therapy.  As part of a multi-disciplinary team, you will work closely with biochemists, bioinformatics and the departments of peptide chemistry, molecular biology and immune monitoring to develop and assess efficacy of this approach.   This position reports to Scientist I, Immunology –  T cell.


Job responsibilities include:


Production of dendritic cells from human PBMC

Culturing of human T cells

Assessment of specificity and functionality of human T cells by multicolor flow cytometry

Analyze multicolor flow cytometry data

Perform scRNA and TCR sequencing as well as data analysis

Track and compile results in an electronic notebook

Assist with the training of lab personnel

Present results to other scientific teams 

 Experience and Essential Skills:


MS in immunology and/ or relevant experience in cancer immunology

A strong background in adaptive immunity in the context of cancer is preferred

3+ years of relevant research experience

Demonstrated experience of flow cytometry and other immune related assays

Ability to work independently, as well as in a collaborative environment to meet project goals

Excellent attention to detail

Excellent written and oral communication skills

Enjoys solving challenging scientific questions in a fast pace environment

Independent, flexible, self-motivated, and the ability to work well with others


If you are ready for the next step in your career and want to work on cutting-edge science in a dynamic, fun environment, please explore our open positions. To apply, please send your resume. In the subject line please note the position for which you are applying.