San Francisco, CA, US

Join us in the most challenging and rewarding science of our lives.


We are seeking a highly skilled and motivated Scientist with expertise in Biophysics to join Nurix’s Discovery team.

You will provide scientific leadership in Nurix’s biophysics efforts to help support our hit identification, hit-to-lead and structural biology efforts. You will play a key role in collecting and interpreting biophysical assay data for ongoing discovery programs, but also will be responsible for implementing novel biophysical assays and techniques to expand our capabilities. You will work closely with an experienced team of interdisciplinary scientists and have regular opportunities to present findings to the project team and senior management.

You should have a strong desire to learn new techniques and incorporate new methodologies into your work. You must be self-driven, resourceful, organized and focused, and enjoy being a part of a dynamic team in a project-based environment solving challenging scientific problems to benefit patients.

Required Qualifications

  • Ph.D. in Biochemistry, Biophysics or a related field with at least three years of post-degree experience, or an M.S. with at least seven years of relevant work experience
  • Experience using biophysical techniques to analyze protein-protein interactions as well as protein-small molecule interactions
  • Hands on experience with Surface Plasmon Resonance (SPR)
  • Expertise with the kinetic and thermodynamic characterization of ligand binding as well as quantitative data management and analysis

Preferred Qualifications

  • Practical experience with biophysical techniques such as Microscale Thermophoresis (MST), Isothermal Titration Calorimetry (ITC), Differential Scanning Fluorimetry (DSF), and Nuclear Magnetic Resonance (NMR)
  • Experience with Fragment Screening

Application Process

Please include a two-page research summary that highlights the above required qualifications along with your resume.