We are seeking a medicinal chemist to contribute to the chemistry efforts for one or more of our drug discovery programs working as part of a cross-functional team. Design of compounds, synthesis within our internal laboratories, collaboration with CROs, and broad general chemistry department support will be key components of the position. This is an outstanding opportunity to learn from experienced medicinal chemists and drug hunters applying structure based-drug design, modern hit-identification strategies (including virtual screening and DEL), and advanced pharmacology to GPCR targets to address unmet medical needs.

REQUIREMENTS 

• Contemporary expertise and understanding of synthetic organic chemistry ranging from modern synthetic methodologies to multi-step synthetic route design, compound purification, and characterization.
• Ability to independently design, execute, and troubleshoot practical synthetic routes towards drug-like molecules.
• Strong analytical thinking and skills to organize and analyze structure activity relationship (SAR) data sets to drive design ideas.
• Ability to learn and leverage computational modeling and SAR analysis tools to design compounds that impact the directions of the program.
• Outstanding communication skills with demonstrated ability to deliver effective presentations.
• Highly collaborative, team-oriented, and considerate of the needs of the team.
• Leadership potential towards managing outside CRO chemistry FTEs.

QUALIFICATIONS

• Ph.D. in synthetic organic chemistry or medicinal chemistry with or without postdoctoral experience (medicinal chemistry experience in biotech/pharmaceutical industry and experience with structure-based drug design is a plus); or a BS / MS with >6 years’ experience in biotech/pharmaceutical industry

The anticipated salary range for candidates who will work in South San Francisco, CA is $120,000 - $145,000. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location and relevant education or training. Septerna's compensation package also includes benefits, stock options, and annual target bonus for full-time positions.