Careers
Principal Research Associate/Scientist, Biology Contractor at Flare Therapeutics
Cambridge, MA, US
To date, the collective research on transcription factors has been elusive to drug discovery. Flare Therapeutics, an early-stage biotech, has now reached a moment of light - with the prospect of forever changing the trajectory of how we treat disease. We are trailblazing the path to transcription factors by intervening at a previously hidden region we have identified as the 'switch site.' Join us and help illuminate the path to the possible.
In this role you will…
- Develop and validate assays with a high degree of independence to drive drug discovery campaigns
- Collaborate with chemistry and biochemistry colleagues to understand the mechanism of action of small molecule modulators of transcription factors to improve compound efficacy for H2L and LO advancement
- Support cell and molecular biology activities across Flare’s early pipeline projects
- Present data and research plans to the teams to inform data-driven decisions
About you…
- You have a BS or MS in molecular or cellular biology
- You have at least 5 years of experience in biotech/pharma post-degree (required)
- You have experience with cell assay development, drug discovery screening and mechanistic studies
- You are experienced in cell engineering (shRNA, CRISPR knockin/knockout, generation of stable lines, viral transduction, etc.)
- You have worked in oncology and/or transcriptional regulation
- You are passionate about science, driven to make a real difference for patients, and maybe you have even been caught reading scientific journals for fun
- You are a proactive individual able to prioritize and balance multiple tasks, meet multiple deadlines, and thrive in a dynamically changing and fast-paced environment
- You thrive on feedback and love collaborating as part of a team
- You have strong communication skills, both written and verbal, including presenting data to internal company meetings